Growing new heart muscle cells

Muscle cells take heart

JCB • VOLUME 169 • NUMBER 1 • 2005 16 Folding in a crowd roteins fold better in a crowd, as predicted by a biophysical model from Margaret Cheung, Dmitri Klimov, and D. Thirumalai (University of Maryland, College Park, MD). Interactions between a protein and large nearby molecules produce repulsive forces at distances that can be as large as the protein itself. The group modeled the energetic e...

Heart Repair Gets New Muscle

Average earth temperatures rose 0.6 oC over the last century, according to the latest Intergovernmental Panel on Climate Change. But that increase pales in comparison to the 1.4–5.8 oC expected increase over this century. As temperatures climb, climate models predict that high-latitude, high-altitude regions like Yellowstone National Park will experience shorter winters and earlier snow melts. ...

Heart Failure: A Growing Problem

Heart Failure: A Growing Problem With 550 000 new cases diagnosed annually and $37 billion spent per year, heart failure (HF) with reduced ejection fraction is one of the largest contributors to disease burden and healthcare expenditure in the United States. Despite significant progress in the treatment of HF with medications, the prognosis of HF remains dismal, with a mortality rate of 42% at ...

Intracellular Mg++ concentrations in vascular smooth muscle cells and heart muscle cells in spontaneously hypertensive rats

Identification of Two Main Independent Components of Fibrillating Heart Muscle

Fibrillation is a hazardous phenomenon in cardiac muscle and so any new work towards the understanding of this process is important to the development of new methods in diagnosis and therapy. In this work we have used surface and intra cardiac ECGs of patients with chronic atrial fibrillation (AF). By means of the blind source separation (BSS) algorithm, which is a well-known method in signal p...